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Peritoneal mesothelioma is also known as abdominal mesothelioma. In simple words, peritoneal mesothelioma relates to cancer of the lining of abdomen and other abdominal structures. It is also the least common type of mesothelioma and occurs only in 30% to 35% of diagnosed cases in 100 to 500 cases normally. The cells of the mesothelium create fluid, but the cancer causes them to overproduce and this creates a lot of fluid causing infection in the abdominal cavity.

Signs and symptoms of mesothelioma depend upon the area of the body which is infected. Pleural mesothelioma or cancer of the lining of the lungs and chest cavity often produce shortness of breath, cough, fever, pain in the lower back, trouble swallowing, and unexplained weight loss and tiredness.